Penile orifice dermatitis should refer to penile dermatitis, penile dermatitis can be dealt with by local treatment, special treatment, systemic treatment and so on. 1. Local treatment: to keep the foreskin, glans clean, local use 1:5000 potassium permanganate soak or wet compress to deal with. 2. Special treatment: if the patient is candida glans circumcision, can be used locally external clotrimazole or ketoconazole and other drugs to deal with; if it is Trichomonas vaginalis infection, can be taken orally metronidazole and other drugs to deal with. 3. Systemic treatment: If the patient’s infection is more serious, or accompanied by necrotizing glans, then the systemic application of cefoperazone and other antibiotics to deal with. It is recommended that when patients have penile dermatitis, they should go to the hospital, clarify the cause of the disease, and deal with it under the guidance of the doctor, do not take the initiative to deal with it, to avoid delaying the condition.