The anterior margin of the T12 vertebral body is depressed and the intervertebral space is not narrowed, indicating that there is a T12 fracture or osteoporosis. 1. T12 fracture: mainly due to the fracture of the 12th thoracic vertebral body and the collapse of the anterior margin. Due to external compression caused by the thoracic 12 vertebral body compression and burst injury. The absence of narrowing of the intervertebral space indicates that the intervertebral disc structure has not been damaged and the intervertebral disc is intact. 2. Osteoporosis: mainly due to the decline in estrogen levels, nutritional deficiencies, aging and other causes of bone density reduction. Osteoporosis will lead to the reduction of bone trabeculae, collapse, etc., thus causing localized fragility fracture, which will appear on the image of the anterior edge of the vertebral body concave. Because osteoporosis does not affect the intervertebral discs, the normal signs of no narrowing of the intervertebral space will be present. If the above situation occurs, it is recommended to go to the hospital in a timely manner to identify the cause of the disease, and under the guidance of the doctor to carry out regular treatment.