Kidney transplant rejection can be divided into hyper-acute, accelerated, acute and chronic types, and whether rejection can be recovered after treatment needs to be specifically analyzed. 1. Hyper-acute rejection: there is no effective treatment, and once it occurs, most of it cannot be reversed. 2. Accelerated rejection: the overall efficacy of the treatment is poor, but the early use of anti-human T-cell immunoglobulin or anti-thymocyte immunoglobulin can improve the patient’s rejection reaction to a certain extent. 3. Acute rejection: If treated in time, recovery is possible. The common treatment is methylprednisolone shock therapy, but for antibody-mediated patients, immunosorbent removal of antibodies or plasma replacement is often needed. 4. Chronic rejection: there is no particularly effective treatment at present, and the principle of treatment is to prevent acute rejection as soon as possible and protect the residual renal function. When kidney transplant rejection occurs, most of the cases can not be treated and recovered, and it is recommended to do a good job of prevention as soon as possible.