Female endocrine obesity can eat orlistat and other drugs to lose weight, should also be active in the treatment of the original disease, endocrine obesity is common in hypothyroidism, polycystic ovary syndrome. 1. Orlistat: Orlistat is suitable for long-term treatment of obesity and overweight people, can specifically inhibit gastrointestinal lipase, thereby reducing fat absorption, to achieve the role of weight loss. The adverse effects of the drug are mainly gastrointestinal reactions, and the contraindications mainly include patients who are allergic to orlistat or any of the components of the drug preparation, and organic obesity. 2. Endocrine diseases: hypothyroidism is due to the thyroid hormone production is too small or the use of disorders caused by low metabolic disease, due to low metabolism may cause obesity, you can take levothyroxine sodium tablets as a substitute for the treatment; polycystic ovary syndrome is mainly manifested as amenorrhea, hirsutism, obesity, infertility, etc., you can take estrogen and other medications under the guidance of a doctor. Female endocrine obesity, it is recommended to consult a doctor in a timely manner, should not be self-medication.