Bleeding for more than ten days after taking medroxyprogesterone acetate tablets belongs to abnormal bleeding, which may be related to uncontrolled endocrine disorders, endometrial abnormality, uterine fibroids and adenomyosis, intrauterine device, pregnancy and so on. 1. Endocrine disorders: some women with endocrine disorders take a small amount of medroxyprogesterone acetate tablets or a short period of time, can not make the uterine lining effectively transformed and normal menstruation, and some will continue to bleed for up to ten days, you need to check to exclude organic lesions and severe anemia, and then follow the doctor’s instructions with hormonal drugs to regulate. 2. Endometrial abnormality: women with endometrial lesions and endometrial polyps, some of them may not have good bleeding control effect by taking medroxyprogesterone acetate tablets, and they may also have persistent bleeding and heavy bleeding, and they need to undergo diagnostic scraping surgery according to the doctor’s prescription. 3. Uterine fibroids or adenomyosis: in some cases, the medication is not effective, and surgery or placement of intrauterine menstrual ring is needed. 4. Intrauterine device (IUD): it can also lead to ineffective medication and prolonged bleeding, requiring removal of the IUD and diagnostic curettage at the same time. 5. Pregnancy: Incomplete abortion or difficult to avoid the abortion of the patient, take medroxyprogesterone acetate tablets are ineffective, will also have bleeding and long time, need to do early examination to clarify.