Whitehead pimples around the mouth are mainly treated with medication, chemotherapy and physical therapy. 1. Drug treatment: whiteheads are a kind of acne, mainly applying retinoic acid drugs, including all-trans retinoic acid cream, adapalene gel, etc. If the effect of simple use is not obvious, you can also use under the guidance of the doctor with benzoyl peroxide, azelaic acid. 2. Chemical treatment: chemical treatment is more commonly used is fruit acid skin resurfacing, fruit acid skin resurfacing is also known as chemical peeling, this treatment can regulate the secretion of sebaceous glands, for mild acne has a very good therapeutic effect. 3. Physical therapy: Physical therapy includes photodynamic therapy, red light irradiation, blue light irradiation, laser irradiation, etc. In addition to killing Propionibacterium acnes, it can also improve the scars left behind. The same disease, the patient’s physical condition is different, different stages of the disease, the treatment method is different, should be standardized treatment under the guidance of the doctor. All of the above medications should be used as prescribed by the doctor.