Swelling of the hand after a fall wrist sprain, can be combined with a fracture of the wrist, according to the specific degree of injury is different, the way to reduce swelling is also different, soft tissue injuries can be appropriate rest, cold compresses, oral celecoxib pain relief, fracture can be manipulated to reset the splint fixation or surgical internal fixation. If there is only pain and swelling of the wrist joint, there is no activity limitation, deformity and other symptoms, mostly soft tissue injury, you can rest appropriately, reduce the wrist joint activities, use ice intermittent cold compresses within 72 hours after the injury, and hot compresses after 72 hours, which is conducive to swelling. If the pain is more obvious, you can use non-steroidal anti-inflammatory drugs such as celecoxib to relieve pain. If there is difficulty in movement, deformity, obvious pressure pain and other symptoms after wrist sprain, it is mostly fractures of ulna, radius and other bones, which can be externally fixed by manipulation and splinting, or can be treated by surgical internal fixation. After the sprain of the wrist joint, if the pain and swelling continue to be unrelieved, it is recommended to consult a doctor in a timely manner, it is recommended to consult a doctor in a timely manner, to clarify the cause of the disease, and to carry out targeted treatment. The use of the above drugs need to follow the doctor’s instructions.