Lupus erythematosus has the potential to be a mild disease for the rest of your life if treated aggressively and rationally. Lupus erythematosus is a chronic, recurrent autoimmune disease caused by autoimmune abnormalities, and can be divided into cutaneous lupus erythematosus and systemic lupus erythematosus. Cutaneous lupus erythematosus lesions are mainly confined to the skin, such as butterfly-shaped erythema on the cheeks; whereas in systemic lupus erythematosus, the lesions may involve multiple organs and systems, and may manifest as lupus nephritis, mental changes, anemia and other changes. Skin lesions of cutaneous lupus erythematosus can mostly subside with treatment. SLE cannot be cured at present, but the progression of the disease can be mitigated through rational treatment. The treatment goal of lupus erythematosus is to improve the symptoms and control the disease, emphasizing early diagnosis and treatment, and adopting individualized treatment according to the specific conditions of patients. As long as timely treatment is given and regular follow-ups are conducted, the disease can be better controlled. Therefore, it is possible for lupus erythematosus to be a mild disease for the rest of one’s life. It is recommended that patients with lupus erythematosus should go to the rheumatology and immunology department or dermatology department of regular hospitals in time and follow the doctor’s instructions for treatment.