High platelet volume generally has the danger of venous thrombosis, numbness of the body as well as pulmonary and cerebral embolism, etc. Patients with high platelet volume should go to the hospital for treatment in time. 1. Venous thrombosis: high platelet volume may cause the blood coagulation mechanism to be impaired, resulting in hypercoagulable state of the blood, causing high values, if the platelet is greater than 1000×10^9/L, resulting in a high risk of thrombosis, and in serious cases, it will be accompanied by hemorrhage and thrombosis, and the hemorrhage may recur. 2. Numbness of the body: due to high platelet volume leads to abnormal bone marrow hematopoiesis, platelet size varies, high platelet value, there may be weakness, dizziness, diarrhea, numbness of the hands and feet and other symptoms appear. 3. Pulmonary and cerebral embolism: high platelet volume will cause elevated blood viscosity, increasing the risk of thrombosis, causing pulmonary embolism and cerebral embolism leading to weakness, dizziness and other undesirable phenomena, and in serious cases, it may be life-threatening. It should be noted that the simple high platelet volume generally has no clinical significance, need to be combined with the platelet value of comprehensive consideration, need to go to the hospital in time to avoid delay, to clarify the specific causes, follow the doctor’s instructions for treatment.