The common causes of cough in five-year-old children include upper respiratory tract infection, cough variant asthma, gastroesophageal reflux disease, airway foreign bodies, etc., need to be targeted according to the cause of the treatment, the choice of appropriate drugs. 1. Upper respiratory tract infections: different drugs should be selected according to the different pathogens for etiological treatment, viral infections are generally supportive treatment, bacterial infections can choose sensitive antibiotics, such as cefixime, etc., mycoplasma and other infections can choose macrolide antibiotics such as azithromycin and so on. For coughing and coughing children can be given drugs such as acetylcysteine for treatment. 2. Cough variant asthma: generally occurs after contact with allergens can appear cough symptoms. Glucocorticoids can be used to control the symptoms, such as budesonide nebulized inhalation to relieve the symptoms. 3. Gastroesophageal reflux disease (GERD): Long-term reflux of gastric acid and gastric contents can irritate the throat and cause irritating cough. Acid-suppressing drugs, such as omeprazole, can be used. 4. Esophageal foreign body: If there is food or exogenous foreign body mistakenly inhaled into the airway caused by cough, medication is generally not necessary, should be promptly to the hospital for examination, through the bronchoscope will be removed. In short, five-year-old children have a cough, should be timely to the hospital, a clear diagnosis under the guidance of the doctor for treatment. All of the above medications should be used under the guidance of a doctor