Pain on the outside of the little toe can be caused by trauma, gout, osteoarthritis and other diseases, which can be treated with medication and other conservative treatments or surgery according to different causes. 1. Trauma: the pain can be caused by local extrusion or friction, etc. When obvious pain occurs, you can use safflower oil, ibuprofen and other medications as prescribed by the doctor. 2. Gout: the above symptoms can also occur, can use colchicine, celecoxib and other drugs, if necessary, can also be used for a short period of time to use prednisone and other hormone drugs, if necessary, can be considered for surgical treatment. 3. Osteoarthritis: when the above symptoms appear, cartilage nutritional drugs such as glucosamine sulfate can be used, combined with non-steroidal anti-inflammatory and analgesic drugs such as ibuprofen, and surgery can be carried out if necessary. Other possible causes of the above symptoms should also be ruled out, and it is recommended to go to the hospital in a timely manner to avoid delaying the condition and not to use drugs blindly.