The cause of gout is still unclear, it may be related to genetic, environmental and other congenital factors, or other diseases, drugs and other secondary causes. 1. Congenital factors: primary gout caused by both genetic and environmental factors is congenital, mostly caused by uric acid excretion disorders, with a certain family susceptibility. 2. Secondary causes: in addition, the occurrence of gout can be secondary to chronic kidney disease, blood disease and malignant tumors after chemotherapy or radiotherapy. If the prolonged use of furosemide, aspirin and other drugs to inhibit uric acid excretion also cause gout. Patients with gout often experience sudden onset of severe pain in one or more joints, mostly at night, as well as redness, swelling, and elevated skin temperature in the joints. The prognosis is usually good with early and standardized treatment. In conclusion, when the diagnosis of gout is clear, it is necessary to actively cooperate with the doctor to carry out standardized treatment, improve the bad habits, and regular follow-up.