Failure of an osteomyelitis wound to heal may be due to factors such as fatty liquefaction, improper medication, and wound infection. It can be relieved by open wound drainage, controlled medication and cephalosporin antibiotics. 1. Fat liquefaction: Because there is more fat at the incision, the high temperature generated during the electrosurgery burns the subcutaneous fat tissue, and aseptic necrosis may occur after the surgery, forming more exudate and affecting the wound healing. It can be relieved by open wound drainage and changing medication diligently. 2. Improper use of medication: Taking large doses of adrenocorticotropic hormone will inhibit the formation of new capillaries, reduce protein synthesis and affect wound healing. The amount of medication can be controlled under the advice of the doctor, and in serious cases, the medication needs to be stopped. 3. Wound infection: after infection, there is a lot of exudate, which will increase the local tension of the wound, and it is easy to rupture and suppuration, thus aggravating the tissue damage and hindering the healing speed. It can be treated by taking cephalosporin antibiotics, such as ceftriaxone, cefoperazone and other drugs as prescribed by the doctor. It is recommended that patients rest in bed, eat a light diet, and avoid wounds in water, if there is any discomfort, consult a doctor in time.