If the patient is taking endocrine drugs for treatment of breast cancer for 2 years, if there is no allergy to the new crown vaccine, and there is no contraindication to vaccination such as infection, fever, or acute onset of breast cancer, he/she is generally allowed to take the new crown vaccine. Breast cancer for 2 years is in the endocrine treatment period, exclude breast cancer metastasis, determine that the patient is in the stable stage of breast cancer, so there is no contraindication to vaccination with the new crown vaccine, and the vaccine will not have an impact on the development of breast cancer. At the same time, it is also necessary to exclude the patient’s allergy to the vaccine, or fever, or the onset of infectious diseases, etc. After excluding the above contraindications to vaccination, the patient can generally be vaccinated. Vaccination has certain side effects, so you need to choose whether or not to be vaccinated according to your own condition under the guidance of a physician.