Meijer syndrome is a muscle tension disorder mainly manifested by blepharospasm and oral-mandibular dystonia, which can be treated by medication, surgery, and botulinum toxin type A injection. 1. Drug treatment: patients can actively eliminate the triggers under the guidance of doctors and use antipsychotics and antiparkinsonian drugs, which can reduce the number of episodes of blepharospasm. At the same time, close attention to complications, such as joint disorders need to be manipulated, such as depression, anxiety and other symptoms, need to be given antipsychotic drugs for psychotherapy. 2. Surgery: If the effect of medication or injections is not obvious, the patient can be treated with brain pacemaker through surgery, but serious complications such as cerebral hemorrhage may occur, and the treatment plan should be chosen according to the condition. Regular follow-up is required after surgery as prescribed by the doctor. 3. Botulinum toxin type A injection treatment: for people with orofacial and mandibular dystonia and people with eye spasms, taking medication along with Botulinum toxin type A injection treatment can alleviate muscle spasms, and the general efficacy of the treatment lasts for 3~6 months. Patients with Meijer syndrome are advised to actively cooperate with their doctors and pay close attention to adverse reactions such as dizziness, fatigue, drowsiness, etc. During drug treatment, if large doses of antipsychotics are used, tremor, ataxia or other serious reactions may occur, so they need to take them strictly in accordance with the dosage required by their doctors and should not change the dosage on their own.