There are many causes of pimples and hard lumps, and different treatment programs should be chosen according to different causes. If boils are treated with anti-inflammatory and anti-infection or surgical drainage, and if nodular itchy rashes are treated with cryotherapy or topical hormone therapy, the main symptoms are redness, swelling, heat and pain. 1. Boils: Boils are a kind of purulent, infectious inflammation of hair follicles and their deep surrounding tissues, mainly caused by Aureobasidium infections, mainly manifested as red, swollen, hot and painful nodules with unclear boundaries. It can be treated with antibiotics such as cephalosporins to fight infection. If the boil has become pus, incision and drainage surgery is feasible for treatment. 2. Nodular itchy rash: Nodular itchy rash is a skin disease with itching and nodules as the main clinical features. Clinically, the hard nodules can be treated with cryotherapy. For mild hyperplasia, glucocorticoid creams such as dexamethasone can be applied to the rash for localized sealing treatment. 3. In addition, “lumps and hard lumps” may also be keloid, dermatofibroma, etc., respectively, can take the local closed or surgical treatment. In conclusion, lumps and bumps should be considered to be caused by different reasons, and it is recommended to consult a doctor in time for the treatment of the cause.