Thickening of the liver parenchymal light spots is a description of how the parenchyma of the liver appears on ultrasonography. It is commonly seen in liver injury caused by fatty liver, alcoholic liver, chronic hepatitis B and cirrhosis. 1. Fatty liver: when suffering from severe fatty liver, due to liver steatosis, liver cells are destroyed, resulting in liver tissue damage, which can be characterized by thickening of liver parenchyma in ultrasonography. 2. Alcoholic liver: alcoholic liver caused by long-term alcohol consumption will cause liver parenchymal damage, and ultrasonography will show thickening of liver parenchymal spots and enlargement of the liver. 3. Chronic hepatitis B: Chronic hepatitis B will cause chronic liver damage if it is not cured for a long time, and ultrasonography can find the thickening of liver parenchymal echogenic spots and liver enlargement, etc. Clinical symptoms often include jaundice, right sidedness of the liver and liver enlargement. Clinical symptoms often include jaundice, right upper abdominal pain, loss of appetite, fatigue and other symptoms. 4. Cirrhosis: Early ultrasonography of cirrhosis firstly shows thickening of liver parenchyma spots, and the edges of the liver can be jagged and changed. It is recommended to go to the hospital in time to check the specific cause and treatment to avoid delaying the condition.