Rash is a common side effect of targeted drugs, which usually disappears with the end of treatment. Rash is one of the common side effects of targeted drugs, which can be manifested as erythematous nodules on the local skin, which can be accompanied by itching and other uncomfortable symptoms, and secondary infections can also cause skin ulceration. Rash caused by targeted drugs has a certain degree of self-healing, with the end of treatment, stop using targeted drugs after the rash can disappear on their own. If the symptoms of the rash are more serious, it can be treated with medication under the guidance of a doctor. If the itching is more intense, it can be relieved by taking anti-allergic drugs such as loratadine internally, and at the same time with anti-itching ointment such as glycerol lotion, etc. For the patients with secondary infections, erythromycin ointment can be applied externally to carry out anti-inflammatory and anti-infective treatments. For rashes caused by targeted drugs, if the symptoms worsen, you need to go to the hospital in time to avoid delaying the condition.