Whether a thyroid nodule of 2 centimeters is serious or not needs to be determined by the specific nature of the nodule. If the nodule is benign, it is usually not serious and close observation is usually sufficient. If the nodule is malignant, it is more serious and requires surgery. 1. Benign nodules: thyroid nodules of 2 cm are benign and asymptomatic and generally not serious, patients should pay attention to a moderate iodine diet in their lives, while following the doctor’s instructions for regular review. 2. Malignant nodules: thyroid nodules 2 cm if there are signs of malignancy, fine needle aspiration biopsy suggests malignant tumors, belonging to the more serious cases, need to be surgically removed as soon as possible. Thyroid nodules are generally benign, and patients are advised to treat them under the guidance of their doctors.