Monkeypox can cause fever, fatigue, rash and other symptoms, treatment needs to be symptomatic treatment, such as cooling treatment, anti-itching treatment. 1. Cooling treatment: if monkeypox causes fever symptoms, you can use physical cooling, take warm water to wipe the body to promote fever. If the fever temperature is high, physical cooling effect is not good, you can use antipyretic and analgesic drugs, such as ibuprofen according to the situation. 2. Antipruritic treatment: patients are prone to rashes, showing itchy skin, you can choose potassium permanganate solution, boric acid solution, etc. to wash the rash or wet compresses. Disease for infectious diseases, need to isolate the treatment. If diagnosed as monkeypox disease, it is recommended that early standardized treatment to reduce the adverse effects of the disease.