Nosebleed after chemotherapy can be first compressed to stop bleeding, and then under the guidance of the doctor according to different reasons to take platelet-raising therapy, hepatoprotective therapy, compression to stop bleeding, environmental humidification and other methods of treatment. 1. Platelet lowering: platelet lowering is a common side effect after chemotherapy, which may lead to easy bleeding of nasal mucosa, in this case, according to the situation, we can apply recombinant human thrombopoietin injection or direct transfusion of platelets to raise platelet therapy to control bleeding, and at the same time, review the blood routine every 2-3 days to know the recovery of platelets. 2. Coagulation disorder: chemotherapeutic drugs often have the side effect of liver injury, which leads to coagulation dysfunction, resulting in nosebleeds, in this case, you can apply liver-protecting drugs, such as polyene phosphatidylcholine injection, to help reduce the occurrence of bleeding, and at the same time, every 5-7 days or so, review the liver function and coagulation function to understand the situation. 3. Nasal mucous membrane dryness: Nasal mucous membrane dryness and rupture may occur after chemotherapy and lead to nosebleed, in this case, you can press to stop bleeding, and then use a humidifier to improve the humidity of the surrounding environment, to keep the nasal cavity comfortable, to avoid bleeding again. There are different causes of nosebleed after chemotherapy, patients are advised to clarify the causes and treat the symptoms under the guidance of doctors.