Gentian Diarrhea Pill and Zhi Bai Di Huang Wan are not recommended to be taken together. Gentian Diarrhea Pill is composed of gentian, chaihu, scutellaria, gardenia, zejia, mouton, psyllium, angelica, dixie and licorice, which has the efficacy of clearing the liver and gallbladder and promoting dampness-heat, and is suitable for patients with the evidence of liver and gallbladder dampness-heat (dampness-heat evils accumulating in the liver and gallbladder), which can be seen as symptoms of reddening of the eyes, dizziness, bitter taste and dryness of the mouth, short and reddish urination (urine with small amount of volume and dark yellow color), and pain in the coarseness of the ribs and the abdomen. It should be used with caution in patients with weak spleen and stomach. Zhi Bai Di Huang Wan contains Radix Rehmanniae Praeparata, Cornu Cervi Pantotrichum, Cornu Cervi Pantotrichum, Chinese yam, Mudan Pi, Poria, Ze Xeroxia, Zhi Mu, and Phellodendron Bark, which are effective in nourishing yin and lowering fire (nourishing the yin essence and lowering the fire). Zhi Bai Di Huang Wan is indicated for patients with yin deficiency and fire (deficiency of yin essence in the body, resulting in hyperactivity of deficiency fire), which can be seen as sore throat, hot flashes (a burst of fever), night sweating (abnormal sweating after going to sleep, sweating stops after waking up), and lumbar and knee soreness and weakness (a feeling of soreness and weakness of the lumbar and knee areas). Zhi Bai Di Huang Wan should be used with caution in patients with fever and solid heat. Gentian Diarrhea and Liver Pill should be used with caution in patients with weak spleen and stomach. Zhi Bai Di Huang Wan should be used with caution in patients with fever of cold and solid heat. They are used to treat solid and deficiency symptoms respectively, and the drug mechanisms are different. If you take these two drugs at the same time may cause adverse reactions. During the use of Gentian Diarrhea Pill and Zhibai Di Huang Pill, avoid spicy and stimulating food, and pay attention to a light diet. Before using the medication, patients are advised to consult their doctors and not to take them together blindly.