Kidney essence deficiency and kidney qi weakness are not the same etiology and clinical manifestations, such as kidney essence deficiency is generally congenital endowment insufficiency (congenital constitution and function is not good), excessive room labor, etc., manifested as developmental delay, premature aging, hypogonadism, etc.; Kidney qi deficiency is caused by the loss of kidney yang, overexertion, uncontrolled sexual intercourse or chronic disease loss of nourishment, the symptoms of slippery semen and premature ejaculation, urinary residual leeching, urination frequency and clear, etc.. Kidney qi deficiency is mostly due to high kidney qi weakness, or young kidney qi is not full, or excessive labor, chronic disease and loss of nourishment, resulting in kidney qi weakness and disease, common waist and knee soreness and softness, frequent and clear urination, urinary residual leaching, or urination, or even incontinence, men with slippery semen and premature ejaculation, women with clear cold, and so on. Kidney essence deficiency is mostly due to innate endowment insufficiency, acquired loss of nourishment, kidney essence is not full; or due to prolonged illness and strain, housework is not in order, depletion of kidney essence caused by the common children’s growth retardation, short, fontanel delayed closure, mental retardation, bone impotence; men’s sperm less infertility, women’s menstruation, infertility, loss of libido. In addition, the lack of kidney essence can also be seen in adults, premature aging, waist and knee weakness (waist and knee weakness), tinnitus and deafness, hair loss, loose teeth, forgetfulness, stagnation, impotence of the feet, slow movement and other manifestations. When discomfort occurs, one should consult a doctor in time and choose medication under the physician’s guidance of identification to avoid delaying the condition.