Low glomerular filtration rate usually suggests renal insufficiency, which may present symptoms such as decreased urine output, increased blood pressure, skin edema, and may present nausea and vomiting, loss of appetite, anemia, and other manifestations of systemic organ system involvement. 1. Decreased urine output: with low glomerular filtration rate and renal insufficiency, the water metabolized in the body cannot be excreted normally, thus the symptom of low urine output occurs. 2. Elevated blood pressure: Due to low glomerular filtration rate and renal insufficiency, the water metabolism of the body is impaired, which leads to sodium and water retention in the blood circulation, and the pressure of elevated blood volume on the blood vessel wall increases, thus resulting in the symptom of elevated blood pressure. 3. Skin edema: due to low glomerular filtration rate, the emergence of renal insufficiency, water and sodium retention in the body, increased urinary protein, resulting in a decrease in plasma osmolality, exudation to the tissue fluid, resulting in skin edema and so on. Low glomerular filtration rate may also lead to other symptoms, it is recommended that patients go to the regular hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.