Peeling and stinging after adapalene gel use can be repaired with skin care products containing hyaluronic acid ingredients and no alcohol, and pay attention to sun protection. Peeling and stinging is a more common local adverse reaction after adapalene gel use, if the degree is mild, usually do not need to stop the drug, can gradually build up tolerance. UV light can increase irritation, so be careful to avoid sunlight during use. Do not use skin care products containing alcohol or exfoliating ingredients when there is peeling and stinging, you can use skin care products containing hyaluronic acid and collagen ingredients to repair. If the use of peeling stinging pain is more serious, or burning sensation, itching, redness and swelling and other allergic reactions, you should stop the drug and wash the local medicine, timely consultation with the doctor, to take to stop the drug, change the drug or reduce the frequency of use of medication and other treatment methods. The use of drugs need to follow the doctor’s advice.