Metformin can be taken in case of insulin resistance, Metformin is effective in improving insulin resistance. It helps peripheral tissues to utilize glucose. For specific dosage, it is recommended to consult your doctor. The main pathogenesis of type 2 diabetes is insulin resistance with relative insulin deficiency. Insulin resistance is always present during the development of type 2 diabetes. Metformin is the first-line oral hypoglycemic agent of choice for the treatment of type 2 diabetes mellitus, which can well improve insulin resistance, reduce fasting and postprandial blood glucose. and increase glucose utilization by peripheral tissues. It is suitable for the initiation of treatment in patients with type 2 diabetes who have substandard blood glucose despite dietary and exercise interventions. This drug is contraindicated in patients with ketoacidosis, hepatic and renal failure, heart failure, myocardial infarction and other diseases, as well as pregnant and lactating women; the drug may cause adverse reactions such as nausea, vomiting, fatigue, dizziness, and lactic acidosis; and may cause hypoglycemia when combined with other types of hypoglycemic drugs. Patients are advised to use it under the guidance of a doctor.