Appropriate masturbation is generally not harmful, if there is weakness, fatigue and other symptoms, quit masturbation after a year the symptoms will improve; if the patient long-term masturbation erectile dysfunction, quit masturbation after a year will not improve the symptoms, the need for drug treatment, surgical treatment. 1. In general, appropriate masturbation is not harmful to the organism. If the patient has symptoms such as weakness, fatigue, mental depression, memory loss, etc. due to long-term masturbation, the uncomfortable symptoms will be relieved after one year of abstinence from masturbation. 2. If a male patient has symptoms of erectile dysfunction such as slow erection and difficulty in erection due to long-term masturbation, the symptoms cannot be improved by quitting masturbation and professional treatment is needed. Patients with erectile dysfunction can take oral sildenafil citrate tablets, tadalafil tablets and other phosphodiesterase 5 inhibitors as prescribed by the doctor, and also oral testosterone propionate tablets, testosterone undecanoate pills and other androgenic hormone treatments; secondly, the patient can also take surgical treatments, such as penile venous fistula surgery, penile prosthesis implantation surgery and other surgical methods. After giving up masturbation for a year, weakness, fatigue and other uncomfortable symptoms will be relieved, but erectile dysfunction and other diseases will not be relieved, it is recommended that patients go to the regular hospital in a timely manner to consult the doctor for treatment.