High plasma renin activity may be caused by hypertension, cirrhosis of the liver, etc., and in the case of female patients, it may also be caused by pregnancy. 1. Hypertension: Hypertension is usually caused by excessive alcohol consumption, long-term anxiety, heredity, etc. Some patients may have some less specific symptoms, such as head swelling and pain, paroxysmal dizziness, numbness of the limbs, etc. If the condition is more serious, renal impairment, blurred vision, loss of consciousness, myocardial infarction, stroke, angina pectoris and other symptoms. 2. Cirrhosis: Cirrhosis is mostly caused by long-term cholestasis, drug stimulation, liver blood circulation disorder, etc. Early stage of cirrhosis usually has no obvious symptoms, but in late stage, patients will have spleen enlargement, ascites, circulatory disorders, etc., accompanied by abdominal pain, diarrhea, weight loss, fever and other symptoms. 3. Pregnancy: high plasma renin activity during pregnancy is normal. If high plasma renin activity occurs, you should go to the hospital for further examination to determine the specific cause of the disease, and follow the doctor’s instructions for treatment after diagnosis.