There are many causes of peritonitis, commonly following trauma, especially injury to the cavernous organs. Injury to the small intestine and injury to the colon can lead to the flow of intestinal contents into the peritoneal cavity, which in the early stages is chemical peritonitis and as the condition evolves, it can lead to bacterial infection and bacterial peritonitis. Patients may also present with significant abdominal pain, nausea, vomiting, and fever. In addition, rupture of the liver or spleen is also seen after trauma, especially if the liver rupture is combined with bile duct injury, and the peritoneal cavity into which bile flows can also induce peritonitis. Patients not only have significant abdominal pain, but also hypotension and shock, and patients with ruptured spleen may also have symptoms of peritonitis. Injuries such as these should be treated with active surgical options, dissection, and repair and, if necessary, excision of substantial organ damage. Repair surgery should also be chosen for cavity organ injuries and postoperative anti-infection treatment.