Wake up early and often mouth ulcers are different situations, the causes are also different. Easy to wake up early can be divided into physiological factors, pathological factors; often mouth ulcers need to consider improper diet, immunity decline and other factors. 1. easy to wake up early causes: ① physiological factors: age aging will lead to the body of melatonin reduction, resulting in a short sleep; drinking coffee before bed, strong tea will also affect sleep; long-term mental stress can also cause easy to wake up early; ② pathologic factors: depression, neurasthenia, cardiopulmonary diseases, etc., will also lead to easy to wake up early. 2. often mouth ulcers cause: ① the patient’s own immunity is reduced, easy to suffer pathogens, resulting in frequent mouth ulcers; ② long-term dieting, picky eating, partiality, etc. or lead to unbalanced nutritional intake, lack of vitamins, trace elements, and thus often mouth ulcers. Or, long-term eating sharp food caused by the mucous membrane scratches. Wake up easily and often mouth ulcers, it is recommended that patients go to the hospital in a timely manner to improve the examination, in accordance with the doctor’s instructions to take standardized treatment, do not ignore the symptoms, do not private treatment, so as not to lead to adverse consequences.