Symptoms of advanced stage of lung cancer vary greatly, and there may be lung symptoms, symptoms of metastatic sites, and complications. 1. Lung symptoms: Lung cancer in the late stage usually has larger lung tumors and the symptoms are more obvious. Symptoms such as coughing, coughing up sputum, blood in sputum, chest tightness, dyspnea, chest pain and so on are often manifested. 2. Symptoms of metastatic site: with bone metastasis, pain in bones of metastatic site and bone fracture in serious cases; with brain metastasis, dizziness, lightheadedness, nausea and other symptoms; with liver metastasis, pain in liver area, loss of appetite, jaundice and other symptoms. When accompanied by mediastinal metastasis compressing the superior vena cava, head, neck and face swelling can appear. 3. Complications: In advanced stage of lung cancer, due to combined infection, tumor consumption and other factors, patients may show fever, emaciation, weight loss, loss of appetite and so on. The prognosis of advanced stage of lung cancer is poor, mainly adopting symptomatic treatment, and those who are physically fit can undergo anti-tumor treatment to delay tumor progression and prolong patients’ survival time. It is suggested that patients should follow the doctor’s advice and standardize the treatment under the guidance of professional doctors to improve the survival period.