Carrying the leber gene does not necessarily lead to the development of the disease. Carrying the leber gene means that the patient carries the gene for leber hereditary optic neuropathy. The disease is inherited in a specific way, with more males than females affected, but the offspring of male patients do not develop the disease, while the offspring of female patients can develop the disease. Females are mostly carriers and their children can develop the disease, with about 50% of sons developing the disease and about 8% to 10% of daughters developing the disease. Therefore, some scholars believe that the disease is cytoplasmically inherited. The cause of the disease is not particularly well established, and not all patients who carry the causative gene develop the disease. Even if the disease develops, the age of onset is uncertain. Some patients develop the disease in their youth or middle age, while others may develop the disease at a much later age, which usually requires genetic testing to confirm the diagnosis.