Pituitary adenoma occupies the third place among intracranial tumors, with an incidence of 1 per 100,000 people and accounting for 7% to 10% of intracranial tumors. Traditional craniotomy and transsphenoidal pituitary adenoma resection carried out under microscope have achieved better results for most patients, but the disadvantages are large surgical trauma, relatively poor visualization, large destruction of nasal structures, many postoperative complications and slow recovery. At present, our department adopts the world’s advanced ventriculoscopic-assisted technique to perform single-nostril transsphenoidal pituitary adenoma resection. This surgery gives full play to the advantages of ventriculoscopy, using the natural channel of the nasal cavity, and the ventriculoscope penetrates deep into the surgical area to observe the anatomical structure of the surgical area at a close distance, making the tumor removal safer and more thorough, significantly reducing postoperative complications, and the surgery is less traumatic, resulting in less postoperative pain and faster recovery for patients. The surgery also leaves no scars, which is a veritable minimally invasive surgery. In addition, this surgery can greatly shorten the patient’s hospital stay and minimize the patient’s hospital costs. It is currently the most ideal method for the treatment of pituitary adenomas.