There are many causes of lateral ventricular plexus calcification in children, both physiologic and pathologic. Pathological changes are mostly seen in hypoparathyroidism, tuberous sclerosis, cerebrofacial angiomatosis, and papilloma of the lateral ventricular choroid plexus, etc. Pathological changes are not only choroid plexus calcifications but also calcifications in other parts of the brain, and hypoparathyroidism is associated with twitching, low blood calcium, and decreased serum parathyroid hormone, but this calcification is mostly symmetrical, including bilateral thalamus. For the differentiation between pathological and physiological, a comprehensive analysis of brain CT, brain MRI and serological examination is required.