The fissures on the heel of the foot are caused by a variety of conditions. 1. Consider local trauma, and it is clinically recommended to use topical iodophor and potassium permanganate solution, as well as topical recombinant bovine basic fibroblast growth factor gel and mupirocin ointment to promote skin repair and prevent infection. 2. Consider hyperkeratotic tinea pedis, and you can usually choose to use topical antifungal creams, such as 5% salicylic acid ointment, terbinafine cream, and miconazole nitrate cream. The most important thing is that you can use a lot of anti-fungal medications, such as terbinafine hydrochloride tablets and itraconazole capsules. 3, consider that it is caused by chancroid eczema, you can choose to use topical compound flumethasone ointment, halometasone cream, 5% salicylic acid ointment, etc. You can take oral antihistamines, such as imipramine extended-release tablets and loratadine citrate tablets.