HPV vaccine is the human papillomavirus vaccine, which is commonly used clinically to prevent diseases caused by human papillomavirus infection. Cervical cancer is a common disease that seriously affects women’s health, and HPV is the main causative factor leading to human cervical cancer. Through HPV vaccination, the human body can be stimulated to produce antibodies to avoid HPV infection to a large extent, greatly reducing the incidence and mortality of cervical cancer. The HPV vaccines that are more commonly used in the market at present include the nine-valent HPV vaccine, four-valent HPV vaccine, and bivalent HPV vaccine. Different HPV vaccines have different adapted populations, and they should be used reasonably under the guidance of doctors.