High cholesterol in thin people may be related to heredity, ageing, endocrine metabolism disorders, the development of some systemic diseases, or the administration of drugs that affect lipid metabolism. Wasting is only one of the factors that affects the decline of cholesterol, so even though some people are thin, they can have elevated cholesterol levels. For example, some people suffer from familial hypercholesterolemia; postmenopausal women may have a gradual increase in cholesterol levels; people with diabetes mellitus, hypothyroidism, myeloma, systemic lupus erythematosus and other diseases may develop secondary hyperlipidemia; and patients taking thiazide diuretics, glucocorticosteroids, such as prednisone and other medications, may also cause hyperlipidemia. When hypercholesterolemia occurs, one should consult a doctor in time, do not abuse drugs, apply lipid-lowering drugs and treat the primary disease under the guidance of a doctor, and try to keep the cholesterol level within the normal range. At the same time, it is necessary to maintain a good diet in daily life and eat less greasy and fried food.