There is no clear indication that chemotherapy should not be given more than four times, and the exact number of chemotherapy treatments should be decided according to the condition. Some diseases are cured by chemotherapy, such as leukemia, before complete remission is achieved, chemotherapy can be continued until complete remission, and after complete remission, consolidation chemotherapy is still needed, with no clear limitation on the number of times. Postoperative adjuvant chemotherapy is to reduce tumor recurrence, usually done 4~6 times. Palliative chemotherapy is to relieve pain and evaluate the efficacy every two weeks. Therefore, the exact number of times chemotherapy is needed is decided according to the disease condition and the purpose of chemotherapy, it is not that it cannot be more than 4 times, the patient should ask the doctor’s opinion, comprehensively evaluate their own disease and physical condition, and choose the appropriate cycle of chemotherapy.