Vaginal itching while sleeping can be caused by vaginitis, diabetes, etc. It is also important to know if it is related to pinworm infection. 1. Vaginitis: Trichomonas vaginitis, Candida vaginitis or Mycoplasma and Chlamydia infections may cause vaginal itching. During the daytime work is busy, itching symptoms are easy to be ignored. Into the night concentration, may feel vaginal itching more serious. 2. Diabetes: diabetic patients own resistance is weak, long-term application of drugs lead to vaginal mold reproduction, is also the main cause of vaginal itching at night. 3. pinworm infection: pinworm infection patients, into the night, pinworms crawl out of the anus to lay eggs. If the pinworms or eggs enter the vagina, it can also cause a significant itching sensation. Sleeping time vaginal itching, the main consideration and gynecological diseases, female friends need to pay attention to keep the vulva clean and dry, wear cotton underwear, etc. If the itching can not be relieved, it is recommended that the hospital gynecology for leukorrhea routine and other examinations, timely and clear diagnosis, active treatment.