The order in which ipratropium bromide and budesonide are used is generally in no particular order. Ipratropium bromide is a drug with bronchodilator effects, which is usually administered by nebulized inhalation, and in combination with inhaled beta agonist drugs can treat reversible airway obstruction caused by asthma and bronchospasm. Budesonide, on the other hand, is an adrenocorticotropic hormone that has been shown to reduce respiratory hyperresponsiveness, inhibit the inflammatory response of the airways, and relieve bronchospasm. Although budesonide and ipratropium bromide can be used in combination, but the two drugs need to be applied separately, as for the order of medication is generally not a clear requirement, the impact is not significant. Adverse reactions: Clinical trials have reported that the most common adverse reactions caused by ipratropium bromide are headache, dry mouth, throat irritation, cough, gastrointestinal dyskinesia, dizziness, nausea and so on. Common adverse reactions caused by budesonide are cough, nosebleed, diarrhea rash. Contraindications: Both the use of Glutethimide and Budesonide should be noted that those who are allergic to the ingredients contained in the drug need to be prohibited. Precautions: In case of unusual adverse drug reactions during the use of the drug, inform the physician promptly. The use of ipratropium bromide as well as budesonide needs to be done in strict compliance with the doctor’s instructions and should never be abused.