Muscle strain injury and soft tissue strain injury are different in terms of etiology, site of onset, symptoms, and treatment. 1. Etiology: Muscle strain injury is often caused by repeated movements over a long period of time and is a chronic cumulative muscle injury. On the other hand, soft tissue strain injury is caused by the direct action of external forces, such as contusion. 2. Pathogenesis: muscle strain is commonly found in the waist, neck and legs. Soft tissue strain injury can be divided into sprain and contusion, sprain is often found in the limbs and joints fascia, contusion mainly occurs in the external force. 3. Symptoms: Muscle strain patients usually show muscle weakness, muscle fatigue, localized soreness and other symptoms. In contrast, soft tissue strains are characterized by swelling and pain, and if the condition is serious, problems such as tendon adhesion and arthritis may occur in later stages. 4. Treatment: Muscle strain injury can usually be relieved by proper rest. If there is inflammation, it is necessary to follow the doctor’s advice and use flurbiprofen gel for treatment. For soft tissue strain, the main drug treatment is mainly based on the common nimesulide, etipirizone hydrochloride tablets, glucocorticoids and so on. In summary, muscle strain and soft tissue strain belong to completely different diseases. Therefore, at the onset of the disease, do not treat it according to your own experience, and you should seek medical treatment as early as possible.