The pathologic manifestation of oral mucosal carcinoma is the proliferation of squamous epithelium to form cancer nests and beads, and the periphery of the nests is connected with connective tissue. Clinically, oral mucosal carcinoma is mostly formed by the proliferation of squamous epithelium. The proliferating epithelium invades into the connective tissue and forms a large number of interconnected cell nests, i.e. cancer nests; in the cancer nests, the keratinization process similar to that of the epidermis takes place, and the whorls formed are called cancer beads, and the periphery of the cancer nests in the basal layer is connected with the mesenchymal stroma of the connective tissue. Oral mucosal cancer refers to a group of epithelial malignant tumors occurring in the oral mucosa, which can be classified as carcinoma of the floor of the mouth, carcinoma of the tongue, carcinoma of the palate, carcinoma of the cheeks and so on according to the site of development. In the early stage, it only manifests as small ulcers and pain symptoms, and then symptoms such as eating discomfort, slurred speech, etc., and in serious cases, it is impossible to extend the tongue out of the oral cavity. Therefore, if the ulcers do not heal for a long time, it should be taken seriously, and it cannot be ruled out that it is an early manifestation of oral cancer, so patients should consult doctor in time to find out the cause.