Is high glutamyl transpeptidase 170 serious?

Elevation of glutamyl transpeptidase to 170 more than three times the normal value should be taken seriously. In normal people, the activity of glutamyl transpeptidase in the blood is usually less than 50 U/L. In acute hepatitis, glutamyl transpeptidase is elevated, and during the recovery period, if all other liver function indexes have returned to normal and glutamyl transpeptidase has not yet returned to normal, it suggests that residual lesions exist in the liver and hepatitis has not yet been cured. If it fluctuates repeatedly or stays at a high level for a long time, it should be considered that hepatitis has a tendency to be transformed into chronic. In chronic light hepatitis and cirrhosis, glutamyl transpeptidase is mostly normal; in chronic moderate and severe hepatitis, glutamyl transpeptidase is often 1~2 times higher than normal; if it continues to rise for a long period of time, it indicates that the disease continues to develop; glutamyl transpeptidase is the most sensitive enzyme suggesting cholestasis and bile duct obstruction. However, the severity of the disease cannot be judged based on a single value, and it is important to consult a specialized department in a timely manner, and ask the doctor to identify the cause of the disease by taking into account the history, clinical manifestations and other auxiliary examination results, and then comply with the doctor’s instructions to avoid delaying the disease. Follow-up consultation is not appropriate during treatment.