We are now conducting research on genetic testing for idiopathic gonadotropin-releasing hormone deficiency (including Kallmann syndrome) and pump replacement therapy for gonadotropin-releasing hormone. Therefore, we welcome patients with gonadal dysgenesis with loss or hyposmia to contact us. In Kallmann syndrome, gonadal hypoplasia is manifested in males by small testicular size and absence of spermatogenesis, and in a few patients by cryptorchidism; in females by primary amenorrhea and infantile type of both internal and external genitalia. Rarely, patients may have a combination of cleft lip, cleft palate, cryptorchidism, deafness, color blindness and renal abnormalities. Serum testosterone (T) levels are low in males and estradiol (E2) levels are low in females. Luteinizing hormone (LH) and follicle stimulating hormone (FSH) were low in both males and females. The patient’s chromosomal examination was normal karyotype. kallmann syndrome showed good or delayed response to GnRH excitation test.