Generally speaking, an increase in left ventricular internal diameter to 61mm is more serious, and the larger the left ventricular enlargement, the more serious the disease. The end-diastolic internal diameter of the left ventricle in normal people is usually between 35 and 55mm, with slightly different reference values for men and women, and is usually clinically derived in echocardiography. When the LV internal diameter increases to 61mm it indicates that severe ventricular remodeling is already present, which is a necessary process for the development of heart failure. The LV internal diameter of 61 mm is enlarged from the standard value, and its ejection capacity may decrease with the enlargement of the heart chambers. Patients with an enlarged left ventricle of 61 mm are advised to seek prompt medical attention to find the primary disease causing the ventricular enlargement and to treat it aggressively to delay further deterioration of cardiac function.