There are many reasons for coughing during the daytime without coughing and coughing at night while lying in bed, such as cough variant asthma, cardiac insufficiency, gastroesophageal reflux disease and so on. For different causes of cough, the treatment method is different. 1. Cough variant asthma: a special type of asthma, mainly manifested as irritating dry cough, mostly at night and early morning episodes, without obvious wheezing, shortness of breath and other symptoms. It can be treated with inhaled glucocorticoids (e.g. budesonide) combined with bronchodilators (e.g. salbutamol). 2. Cardiac insufficiency: lying in bed at night and coughing is mainly due to the change of body position, resulting in blood stagnation in the lungs, causing pulmonary stasis and edema, which causes coughing in the middle of the night, and the symptoms can be alleviated by adopting the sitting position. 3. Gastroesophageal reflux disease (GERD): lying down, acidic reflux may reflux to the throat, stimulate the throat, trachea, causing coughing in the middle of the night, pharyngeal discomfort and other symptoms. Coughing can be reduced by inhibiting gastric acid secretion such as omeprazole and promoting gastric motility such as domperidone. There are many reasons why you don’t cough during the day and cough when you lie down on the bed at night, you should go to the hospital in time to clarify the cause of the disease, and treat it under the guidance of the doctor, so as to avoid delaying the condition. The drugs appearing above also need to be used under the guidance of a doctor.