Occlusal pain can be the result of conditions such as mumps, trigeminal neuralgia, and temporomandibular joint disorder syndrome. 1. Mumps: usually caused by mumps virus infection. Most of the patients do not have obvious precursor symptoms, only some of the patients may have symptoms such as lack of appetite, headache, muscle pain, etc., and will also appear in about 1~2 days of parotid swelling and pain, which may be accompanied by localized burning phenomenon, may also be manifested as occlusal muscle pain. Part of the patients may also be accompanied by jaw swelling, sublingual swelling and so on. 2. Trigeminal neuralgia: the pathogenesis is not clear, generally primary trigeminal neuralgia is considered to be related to nerve injury, mental stress, immunity, genetics and other factors, while secondary trigeminal neuralgia can be related to inflammation, trauma, tumors and other factors. Patients often experience recurring cut-like, electric shock-like or tear-like pain, and can also experience trigeminal neuralgia. Some of the severe episodes are accompanied by facial flushing, tearing, streaming, and muscle twitching on the same side, and secondary trigeminal neuralgia patients have longer episodes. 3. Temporomandibular joint disorder syndrome: the cause of the disease is not fully elucidated, may be related to masticatory muscle disorders, inflammatory diseases, osteoarthropathy, joint structure disorders and other factors. Patients often experience pain when opening and closing their mouths, as well as joint popping, and they also experience pain in the masticatory muscles after waking up in the morning when grinding or clenching their teeth. It is recommended that when the symptoms of occlusal muscle pain occur, the cause of the disease should be clarified in a timely manner, and reasonable treatment measures should be taken in accordance with the doctor’s instructions.