Dry palms may be caused by dry climate, skin barrier destruction, palmoplantar keratosis and other reasons. 1. Dry climate: When the weather is too dry and the hands sweat less, it is easy to cause the loss of moisture in the skin of the palms, thus inducing dry palms. External use of urea cream, petroleum jelly for moisturizing, the symptoms can be effectively relieved. 2. Skin barrier damage: If the usual contact with some strong alkaline substances or organic solvents will destroy the sebaceous membrane of the palms of the hands, when a large amount of water loss of the hands, it will lead to dry hands. If you need to contact with strong alkaline substances or organic solvents, you can wear rubber gloves to reduce the chances of skin barrier destruction. 3. Palmoplantar keratosis: This is a skin disease characterized by thickening and keratinization of the skin of the palm and plantar areas, which can lead to dryness of the palms and soles of the feet, and can be classified into two categories: hereditary and acquired. Hereditary palmoplantar keratosis is more common and occurs at birth or shortly after birth. Acquired keratosis palmoplantaris, which usually develops in adulthood, is mainly caused by friction or secondary infections, and cannot be excluded in combination with tumors in the body. However, either type of palmoplantar keratosis can be treated with tazarotene and adapalene. When the patient has dry palms, after excluding physiological causes, it is necessary to go to the hospital in time, to clarify the diagnosis, and follow the doctor’s instructions for treatment.