Painkiller tablets and ibuprofen generally cannot be taken together. Painkillers belong to the compound preparation of antipyretic and analgesic drugs, containing phenobarbital, finasteride, aminopyrine, caffeine and other ingredients, finasteride, aminopyrine has the effect of regulating body temperature and relieving pain. Ibuprofen belongs to non-steroidal anti-inflammatory drugs, and its mechanism of action is similar to that of finasteride and aminopyrine. Taken together can easily cause drug overdose, aggravate side effects, bring nausea, vomiting and other gastrointestinal reactions, damage to liver function, kidney function, and even able to affect the blood system, resulting in coagulation dysfunction and other hazards. If you need to take painkillers and ibuprofen at the same time due to illness, you should be instructed by a doctor and not use the drugs blindly.