Knee replacement hematogenous infection needs to be treated according to the time and severity of the infection. If the time of infection is relatively short, within one month of the knee replacement hematogenous infection, you can choose to carry out debridement treatment to remove the harmful substances in the joint cavity, to avoid worsening of the symptoms of infection. If the infection lasts for a longer period of time, more than one month, it may not be possible to keep the knee prosthesis, and it is best to seek medical attention in time to remove the knee prosthesis, and at the same time to carry out debridement treatment to control the infection, and then carry out knee revision after the infection is completely controlled. Although the probability of blood-borne infection in knee replacement is relatively low, it is still necessary to observe the physical symptoms to avoid infection.